Genetic Disorders


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HFE 3 Mutations, code AC062

Code: AC062

KIT Name: HFE 3 Mutations

Description: The device provides reagents for the identification of exon 4 HFE gene sequence, through the amplification of target sequences, reverse-hybridization and color development. Hemochromatosis (HH) is a disorder of iron metabolism. The disease is determined by inappropriately high absorption of iron by the gastrointestinal mucosa resulting in a progressive accumulation in important organs such as liver, pancreas, heart. Hereditary HH is due to genetic alterations whose effect is to cause excessive absorption of iron by the intestine, resulting in the accumulation of this metal in other organs and tissues. The test detects the H63D, S65C and C282Y mutations.

Extraction: AA1001

Detection: RDB on Strip

Test: 25

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