Genetic Predispositions

MTHFR (C677T) Real Time (FRET), code AA901

Code AA785

KIT Name: MTHFR (C677T) TaqMan Real Time

Description: Kit provides reagents for the genotyping of MTHFR C677T through the amplification of target sequences and allelic discrimination test. Uracil-DNA glycosylase (UNG) enzyme to prevent contamination.
Reduced activity of Methylenetetrahydrofolate reductase leads to high homocysteine levels in plasma. In the sequence of the coding gene a polymorphism (C>T substitution) has been detected in position 677; with consequent MTHFR reduced activity. High levels of homocysteine in plasma represent a risk factor for thrombotic episodes related to the arterious system, but in association with Factor V Leiden and/or Prothrombin 20210 variants lead to an increased risk for venous thromboembolism.

Platforms: 
BioRad - CFX96
Qiagen - RotorGene Q
Applied Biosystems - 7500 Fast

Extraction: AA1001, AA1319/96

Detection: Real Time

Test: 48

Leaflet Coagualtion Kits - ENG Download
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