Genetic Predispositions

MTHFR (C677T) Real Time (FRET), cod. AA901

Cod. AA901

KIT Name: MTHFR (C677T) Real Time (FRET)

Description: Kit provides reagents for the genotyping of MTHFR C677T through the amplification of target sequences and melting curve analysis. Reduced activity of Methylenetetrahydrofolate reductase leads to high homocysteine levels in plasma. In the sequence of the coding gene a polymorphism (C>T substitution) has been detected in position 677; with consequent MTHFR reduced activity. High levels of homocysteine in plasma represent a risk factor for thrombotic episodes related to the arterious system, but in association with Factor V Leiden and/or Prothrombin 20210 variants lead to an increased risk for venous thromboembolism.

Platforms: 
Corbett Research / Qiagen - RotorGene
Stratagene - MX3005P
BioRad - CFX96

Extraction: AA1001, AA898

Detection: Real Time

test: 25

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