Cod. AA831
KIT Name: Factor II Real Time (FRET)
Description: Kit provides reagents for the genotyping of coagulation Factor II (Prothrombin) sequence gene, which includes mutation G20210A, through the amplification of target sequences and melting curve analysis.
One of the most studied factors for the evaluation of thrombotic risk is Prothrombin also called Coagulation Factor II which has a main role in the coagulation cascade since prothrombin activation leads to the transformation of fibrinogen to fibrin with consequent clot formation. A mutation (G20210A) linked to high levels of activated prothrombin with consequent increased risk of venous thrombosis was identified in the 3’-UTR of the coding gene.
Platforms:
Corbett Research / Qiagen - RotorGene
BioRad - CFX96
Extraction: AA1001, AA898
Detection: Real Time
test: 50
